藥物交互作用
Anagrelide + Caplacizumab
嚴重程度: 嚴重
Anagrelide and Caplacizumab: major interaction.
最後更新
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摘要
Caplacizumab blocks von Willebrand factor-mediated platelet adhesion and anagrelide reduces platelet aggregation and count, so together they may increase the risk of serious bleeding. Bleeding is the main adverse effect of caplacizumab.
用白話說明這項交互作用的意義
Anagrelide and Caplacizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Caplacizumab belongs to Cardiovascular.
為什麼會發生
Additive impairment of primary hemostasis through different antiplatelet pathways.
處置方式
Avoid combined use where possible; if anagrelide must be continued, monitor closely for bleeding and check platelet count and hemoglobin. Hold therapy as advised in caplacizumab labeling if significant bleeding occurs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Anagrelide 的其他交互作用
Caplacizumab 的其他交互作用
常見問題
Can I take Anagrelide with Caplacizumab?
MediHelp rates the interaction as major. Anagrelide and Caplacizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Caplacizumab blocks von Willebrand factor-mediated platelet adhesion and anagrelide reduces platelet aggregation and count, so together they may increase the risk of serious bleeding. Bleeding is the main adverse effect of caplacizumab.
How serious is the interaction between Anagrelide and Caplacizumab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combined use where possible; if anagrelide must be continued, monitor closely for bleeding and check platelet count and hemoglobin. Hold therapy as advised in caplacizumab labeling if significant bleeding occurs.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
