藥物交互作用
Abciximab + Caplacizumab
嚴重程度: 嚴重
Abciximab and Caplacizumab: major interaction.
最後更新
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摘要
Caplacizumab blocks von Willebrand factor-platelet binding and abciximab blocks platelet aggregation, so combined use increases bleeding risk. Serious bleeding including mucosal and intracranial hemorrhage is possible.
用白話說明這項交互作用的意義
Abciximab and Caplacizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Abciximab belongs to Cardiovascular; Caplacizumab belongs to Cardiovascular.
為什麼會發生
Additive inhibition of platelet adhesion (anti-vWF A1 domain) and aggregation (GP IIb/IIIa blockade).
處置方式
Avoid the combination where possible; if necessary, monitor closely for bleeding and withhold caplacizumab if clinically significant bleeding occurs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Abciximab 的其他交互作用
Caplacizumab 的其他交互作用
常見問題
Can I take Abciximab with Caplacizumab?
MediHelp rates the interaction as major. Abciximab and Caplacizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Caplacizumab blocks von Willebrand factor-platelet binding and abciximab blocks platelet aggregation, so combined use increases bleeding risk. Serious bleeding including mucosal and intracranial hemorrhage is possible.
How serious is the interaction between Abciximab and Caplacizumab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible; if necessary, monitor closely for bleeding and withhold caplacizumab if clinically significant bleeding occurs.
What other medicines interact with Abciximab?
MediHelp also lists interactions of Abciximab with, for example, Abrocitinib, Acalabrutinib, Acetylsalicylic acid. The full list is on the Abciximab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
