藥物交互作用
Aprepitant + Isavuconazole
嚴重程度: 中度
Aprepitant and Isavuconazole: moderate interaction.
最後更新
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摘要
Aprepitant is a weak CYP3A4 inducer and may modestly lower isavuconazole levels. Reduced antifungal exposure could affect treatment of invasive fungal infection.
用白話說明這項交互作用的意義
Aprepitant and Isavuconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aprepitant belongs to Gastrointestinal Tract; Isavuconazole belongs to Anti Fungals.
為什麼會發生
Weak induction of CYP3A4 by aprepitant increases isavuconazole clearance.
處置方式
Monitor clinical response and consider isavuconazole levels if available.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Isavuconazole 的其他交互作用
Aprepitant 的其他交互作用
常見問題
Can I take Aprepitant with Isavuconazole?
MediHelp rates the interaction as moderate. Aprepitant and Isavuconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aprepitant is a weak CYP3A4 inducer and may modestly lower isavuconazole levels. Reduced antifungal exposure could affect treatment of invasive fungal infection.
How serious is the interaction between Aprepitant and Isavuconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response and consider isavuconazole levels if available.
What other medicines interact with Isavuconazole?
MediHelp also lists interactions of Isavuconazole with, for example, Carbamazepine, Efavirenz, Etravirine. The full list is on the Isavuconazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
