藥物交互作用
Arformoterol + Propranolol
嚴重程度: 嚴重
Arformoterol and Propranolol: major interaction.
最後更新 來源: US FDA label
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摘要
Propranolol antagonizes the bronchodilating effect of arformoterol and may provoke bronchospasm in patients with airway disease. The therapeutic effect of the long-acting beta agonist may be lost.
用白話說明這項交互作用的意義
Arformoterol and Propranolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arformoterol belongs to Respiratory; Propranolol belongs to Cardiovascular.
為什麼會發生
Non-selective beta-2 receptor blockade by propranolol competitively antagonizes arformoterol.
處置方式
Avoid the combination; if a beta-blocker is required, choose a cardioselective agent and monitor respiratory function.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
參考資料
Propranolol 的其他交互作用
Arformoterol 的其他交互作用
常見問題
Can I take Arformoterol with Propranolol?
MediHelp rates the interaction as major. Arformoterol and Propranolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Propranolol antagonizes the bronchodilating effect of arformoterol and may provoke bronchospasm in patients with airway disease. The therapeutic effect of the long-acting beta agonist may be lost.
How serious is the interaction between Arformoterol and Propranolol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; if a beta-blocker is required, choose a cardioselective agent and monitor respiratory function.
What other medicines interact with Propranolol?
MediHelp also lists interactions of Propranolol with, for example, Thioridazine, Acebutolol, Adrenaline-articaine. The full list is on the Propranolol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
