藥物交互作用
Arsenic trioxide + Formoterol
嚴重程度: 嚴重
Arsenic trioxide and Formoterol: major interaction.
最後更新
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摘要
Arsenic trioxide markedly prolongs the QT interval and can cause torsades de pointes. Formoterol adds QT and hypokalemic effects, which raises arrhythmic risk.
用白話說明這項交互作用的意義
Arsenic trioxide and Formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arsenic trioxide belongs to Oncology; Formoterol belongs to Respiratory.
為什麼會發生
Additive QT prolongation, with beta-2 agonist hypokalemia increasing susceptibility.
處置方式
Avoid if alternatives exist; otherwise obtain baseline and serial ECGs and keep potassium and magnesium in the normal range.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Formoterol 的其他交互作用
Arsenic trioxide 的其他交互作用
常見問題
Can I take Arsenic trioxide with Formoterol?
MediHelp rates the interaction as major. Arsenic trioxide and Formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Arsenic trioxide markedly prolongs the QT interval and can cause torsades de pointes. Formoterol adds QT and hypokalemic effects, which raises arrhythmic risk.
How serious is the interaction between Arsenic trioxide and Formoterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if alternatives exist; otherwise obtain baseline and serial ECGs and keep potassium and magnesium in the normal range.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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