藥物交互作用
Amisulpride + Formoterol
嚴重程度: 嚴重
Amisulpride and Formoterol: major interaction.
最後更新
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摘要
Amisulpride prolongs the QT interval in a dose-related way, and formoterol can add to this through tachycardia and hypokalemia. Together they raise the risk of torsades de pointes, especially with electrolyte disturbances or cardiac disease.
用白話說明這項交互作用的意義
Amisulpride and Formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Formoterol belongs to Respiratory.
為什麼會發生
Additive QT prolongation, with beta-2 agonist-induced hypokalemia increasing proarrhythmic risk.
處置方式
Correct potassium and magnesium before use and obtain a baseline and follow-up ECG. Consider an alternative bronchodilator in patients with other QT risk factors.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Formoterol 的其他交互作用
Amisulpride 的其他交互作用
常見問題
Can I take Amisulpride with Formoterol?
MediHelp rates the interaction as major. Amisulpride and Formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amisulpride prolongs the QT interval in a dose-related way, and formoterol can add to this through tachycardia and hypokalemia. Together they raise the risk of torsades de pointes, especially with electrolyte disturbances or cardiac disease.
How serious is the interaction between Amisulpride and Formoterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct potassium and magnesium before use and obtain a baseline and follow-up ECG. Consider an alternative bronchodilator in patients with other QT risk factors.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amitriptyline. The full list is on the Formoterol page.
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