藥物交互作用
Atidarsagene autotemcel + Hepatitis A vaccine inactivated
嚴重程度: 中度
Atidarsagene autotemcel and Hepatitis A vaccine inactivated: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Atidarsagene autotemcel is a gene therapy given after myeloablative conditioning, leaving patients with a temporarily absent or recovering immune system. Vaccines given around this period may be ineffective, and their safety has not been studied.
用白話說明這項交互作用的意義
Atidarsagene autotemcel and Hepatitis A vaccine inactivated can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atidarsagene autotemcel belongs to Miscellaneous; Hepatitis A vaccine inactivated belongs to Anti Virals.
為什麼會發生
Pharmacodynamic: myeloablative conditioning and hematologic reconstitution impair the immune response to vaccination.
處置方式
Give vaccines, where feasible, before myeloablative conditioning and avoid vaccination in the 6 weeks before conditioning. Postpone further vaccination until hematologic recovery, then revaccinate as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Hepatitis A vaccine inactivated 的其他交互作用
- Adalimumab + Hepatitis A vaccine inactivated 中度
- Alefacept + Hepatitis A vaccine inactivated 中度
- Anakinra + Hepatitis A vaccine inactivated 中度
- Anti-thymocyte + Hepatitis A vaccine inactivated 中度
- Antithymocyte globulin equine + Hepatitis A vaccine inactivated 中度
- Antithymocyte globulin rabbit + Hepatitis A vaccine inactivated 中度
Atidarsagene autotemcel 的其他交互作用
常見問題
Can I take Atidarsagene autotemcel with Hepatitis A vaccine inactivated?
MediHelp rates the interaction as moderate. Atidarsagene autotemcel and Hepatitis A vaccine inactivated can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atidarsagene autotemcel is a gene therapy given after myeloablative conditioning, leaving patients with a temporarily absent or recovering immune system. Vaccines given around this period may be ineffective, and their safety has not been studied.
How serious is the interaction between Atidarsagene autotemcel and Hepatitis A vaccine inactivated?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give vaccines, where feasible, before myeloablative conditioning and avoid vaccination in the 6 weeks before conditioning. Postpone further vaccination until hematologic recovery, then revaccinate as needed.
What other medicines interact with Hepatitis A vaccine inactivated?
MediHelp also lists interactions of Hepatitis A vaccine inactivated with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Hepatitis A vaccine inactivated page.
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