藥物交互作用
Atidarsagene autotemcel + Pneumococcal vaccine 13-valent
嚴重程度: 中度
Atidarsagene autotemcel and Pneumococcal vaccine 13-valent: moderate interaction.
最後更新
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摘要
Atidarsagene autotemcel involves myeloablative conditioning followed by hematologic reconstitution, during which immune responses to vaccines are unreliable. Vaccine safety and effectiveness around this therapy have not been studied. Vaccination close to conditioning may be ineffective and confound assessment of adverse events.
用白話說明這項交互作用的意義
Atidarsagene autotemcel and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atidarsagene autotemcel belongs to Miscellaneous; Pneumococcal vaccine 13-valent belongs to Miscellaneous.
為什麼會發生
Myeloablative conditioning and hematopoietic reconstitution impair immune response to vaccination.
處置方式
Give age-appropriate vaccines, including pneumococcal, before conditioning (not within about 6 weeks before it). Defer vaccination until hematologic recovery after treatment.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pneumococcal vaccine 13-valent 的其他交互作用
- Adalimumab + Pneumococcal vaccine 13-valent 中度
- Alefacept + Pneumococcal vaccine 13-valent 中度
- Anakinra + Pneumococcal vaccine 13-valent 中度
- Anti-thymocyte + Pneumococcal vaccine 13-valent 中度
- Antithymocyte globulin equine + Pneumococcal vaccine 13-valent 中度
- Antithymocyte globulin rabbit + Pneumococcal vaccine 13-valent 中度
Atidarsagene autotemcel 的其他交互作用
常見問題
Can I take Atidarsagene autotemcel with Pneumococcal vaccine 13-valent?
MediHelp rates the interaction as moderate. Atidarsagene autotemcel and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atidarsagene autotemcel involves myeloablative conditioning followed by hematologic reconstitution, during which immune responses to vaccines are unreliable. Vaccine safety and effectiveness around this therapy have not been studied. Vaccination close to conditioning may be ineffective and confound assessment of adverse events.
How serious is the interaction between Atidarsagene autotemcel and Pneumococcal vaccine 13-valent?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give age-appropriate vaccines, including pneumococcal, before conditioning (not within about 6 weeks before it). Defer vaccination until hematologic recovery after treatment.
What other medicines interact with Pneumococcal vaccine 13-valent?
MediHelp also lists interactions of Pneumococcal vaccine 13-valent with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Pneumococcal vaccine 13-valent page.
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