藥物交互作用
Atracurium + Oxytetracycline
嚴重程度: 中度
Atracurium and Oxytetracycline: moderate interaction.
最後更新
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摘要
Tetracyclines have weak neuromuscular blocking effects, and potentiation of nondepolarising blockers is described mainly in case reports. Clinical significance with oxytetracycline is likely small but could prolong recovery.
用白話說明這項交互作用的意義
Atracurium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atracurium belongs to Musculoskeletal; Oxytetracycline belongs to Anti Bacterial.
為什麼會發生
Possible calcium chelation and weak presynaptic neuromuscular blockade adding to nondepolarising blockade.
處置方式
Monitor neuromuscular function with train-of-four during surgery or ICU use. Adjust atracurium dosing to response.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Atracurium 的其他交互作用
Oxytetracycline 的其他交互作用
常見問題
Can I take Atracurium with Oxytetracycline?
MediHelp rates the interaction as moderate. Atracurium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tetracyclines have weak neuromuscular blocking effects, and potentiation of nondepolarising blockers is described mainly in case reports. Clinical significance with oxytetracycline is likely small but could prolong recovery.
How serious is the interaction between Atracurium and Oxytetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with train-of-four during surgery or ICU use. Adjust atracurium dosing to response.
What other medicines interact with Atracurium?
MediHelp also lists interactions of Atracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Atracurium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
