藥物交互作用
Atropine + Bethanechol
嚴重程度: 中度
Atropine and Bethanechol: moderate interaction.
最後更新
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摘要
Atropine is a competitive muscarinic antagonist and directly opposes the muscarinic agonist effects of bethanechol on the bladder, gut and other organs. Bethanechol may therefore lose its efficacy, and atropine can be used to reverse bethanechol toxicity.
用白話說明這項交互作用的意義
Atropine and Bethanechol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Bethanechol belongs to Gastrointestinal Tract.
為什麼會發生
Pharmacodynamic antagonism at muscarinic receptors.
處置方式
Avoid routine co-administration because therapeutic effect is lost; if bethanechol overdose or cholinergic toxicity occurs, atropine is the appropriate antidote.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Bethanechol 的其他交互作用
Atropine 的其他交互作用
常見問題
Can I take Atropine with Bethanechol?
MediHelp rates the interaction as moderate. Atropine and Bethanechol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atropine is a competitive muscarinic antagonist and directly opposes the muscarinic agonist effects of bethanechol on the bladder, gut and other organs. Bethanechol may therefore lose its efficacy, and atropine can be used to reverse bethanechol toxicity.
How serious is the interaction between Atropine and Bethanechol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine co-administration because therapeutic effect is lost; if bethanechol overdose or cholinergic toxicity occurs, atropine is the appropriate antidote.
What other medicines interact with Bethanechol?
MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Fesoterodine, Oxybutynin. The full list is on the Bethanechol page.
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