藥物交互作用
Atropine + Dicyclomine
嚴重程度: 中度
Atropine and Dicyclomine: moderate interaction.
最後更新
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摘要
Both drugs are antimuscarinic agents, so their effects add together. Patients may develop dry mouth, blurred vision, urinary retention, constipation, tachycardia, confusion and heat intolerance, particularly the elderly.
用白話說明這項交互作用的意義
Atropine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Dicyclomine belongs to Respiratory.
為什麼會發生
Additive blockade of muscarinic acetylcholine receptors.
處置方式
Avoid routine duplication of antimuscarinic therapy; if both are needed, use the lowest effective doses and monitor for anticholinergic toxicity such as urinary retention, delirium and tachycardia.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Dicyclomine 的其他交互作用
Atropine 的其他交互作用
常見問題
Can I take Atropine with Dicyclomine?
MediHelp rates the interaction as moderate. Atropine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are antimuscarinic agents, so their effects add together. Patients may develop dry mouth, blurred vision, urinary retention, constipation, tachycardia, confusion and heat intolerance, particularly the elderly.
How serious is the interaction between Atropine and Dicyclomine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine duplication of antimuscarinic therapy; if both are needed, use the lowest effective doses and monitor for anticholinergic toxicity such as urinary retention, delirium and tachycardia.
What other medicines interact with Dicyclomine?
MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
