藥物交互作用
Atropine iv / + Glycopyrronium
嚴重程度: 中度
Atropine iv / and Glycopyrronium: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Both are antimuscarinics, so their combination adds to anticholinergic effects including tachycardia, dry mouth, urinary retention and reduced gut motility. This is often intentional perioperatively but can lead to excessive effects.
用白話說明這項交互作用的意義
Atropine iv / and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive muscarinic receptor blockade.
處置方式
Avoid unnecessary duplication; monitor heart rate, and watch for urinary retention, ileus and delirium, particularly in elderly patients.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Glycopyrronium 的其他交互作用
常見問題
Can I take Atropine iv / with Glycopyrronium?
MediHelp rates the interaction as moderate. Atropine iv / and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinics, so their combination adds to anticholinergic effects including tachycardia, dry mouth, urinary retention and reduced gut motility. This is often intentional perioperatively but can lead to excessive effects.
How serious is the interaction between Atropine iv / and Glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary duplication; monitor heart rate, and watch for urinary retention, ileus and delirium, particularly in elderly patients.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Glycopyrronium page.
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