藥物交互作用
Amantadine + Glycopyrronium
嚴重程度: 中度
Amantadine and Glycopyrronium: moderate interaction.
最後更新
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摘要
Both drugs have anticholinergic activity, and their combination may intensify dry mouth, constipation, urinary retention, blurred vision and confusion. Older patients are especially vulnerable.
用白話說明這項交互作用的意義
Amantadine and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amantadine belongs to Anti Virals; Glycopyrronium belongs to Respiratory.
為什麼會發生
Additive anticholinergic pharmacodynamic effects.
處置方式
Monitor for anticholinergic effects such as urinary retention, constipation and confusion, and reduce doses or stop one drug if they develop.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Glycopyrronium 的其他交互作用
Amantadine 的其他交互作用
常見問題
Can I take Amantadine with Glycopyrronium?
MediHelp rates the interaction as moderate. Amantadine and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have anticholinergic activity, and their combination may intensify dry mouth, constipation, urinary retention, blurred vision and confusion. Older patients are especially vulnerable.
How serious is the interaction between Amantadine and Glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects such as urinary retention, constipation and confusion, and reduce doses or stop one drug if they develop.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Glycopyrronium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。