藥物交互作用
Baloxavir marboxil + Magnesium hydroxide
嚴重程度: 中度
Baloxavir marboxil and Magnesium hydroxide: moderate interaction.
最後更新
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摘要
Baloxavir can chelate polyvalent cations such as magnesium in the gut, which may reduce its absorption and antiviral exposure. This could lessen treatment effectiveness for influenza.
用白話說明這項交互作用的意義
Baloxavir marboxil and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Baloxavir marboxil belongs to Anti Virals; Magnesium hydroxide belongs to Gastrointestinal Tract.
為什麼會發生
Chelation of baloxavir by polyvalent cations in the gastrointestinal tract reduces absorption.
處置方式
Avoid taking baloxavir with magnesium-containing antacids or laxatives. If needed, give baloxavir at least 2 hours apart from the antacid.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium hydroxide 的其他交互作用
Baloxavir marboxil 的其他交互作用
常見問題
Can I take Baloxavir marboxil with Magnesium hydroxide?
MediHelp rates the interaction as moderate. Baloxavir marboxil and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Baloxavir can chelate polyvalent cations such as magnesium in the gut, which may reduce its absorption and antiviral exposure. This could lessen treatment effectiveness for influenza.
How serious is the interaction between Baloxavir marboxil and Magnesium hydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking baloxavir with magnesium-containing antacids or laxatives. If needed, give baloxavir at least 2 hours apart from the antacid.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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