藥物交互作用
Gemifloxacin + Magnesium hydroxide
嚴重程度: 嚴重
Gemifloxacin and Magnesium hydroxide: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Magnesium-containing antacids chelate gemifloxacin and reduce its absorption, risking subtherapeutic antibiotic levels.
用白話說明這項交互作用的意義
Gemifloxacin and Magnesium hydroxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Gemifloxacin belongs to Anti Bacterial; Magnesium hydroxide belongs to Gastrointestinal Tract.
為什麼會發生
Chelation of gemifloxacin by magnesium cations in the gut reduces absorption.
處置方式
Give gemifloxacin at least 2 hours before or 3 hours after magnesium hydroxide.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Magnesium hydroxide 的其他交互作用
Gemifloxacin 的其他交互作用
常見問題
Can I take Gemifloxacin with Magnesium hydroxide?
MediHelp rates the interaction as major. Gemifloxacin and Magnesium hydroxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium-containing antacids chelate gemifloxacin and reduce its absorption, risking subtherapeutic antibiotic levels.
How serious is the interaction between Gemifloxacin and Magnesium hydroxide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give gemifloxacin at least 2 hours before or 3 hours after magnesium hydroxide.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Levofloxacin. The full list is on the Magnesium hydroxide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
