藥物交互作用
Belatacept + Certolizumab pegol
嚴重程度: 嚴重
Belatacept and Certolizumab pegol: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Both agents suppress immune function, so combining them raises the risk of serious infections and possibly malignancy, including post-transplant lymphoproliferative disorder with belatacept.
用白話說明這項交互作用的意義
Belatacept and Certolizumab pegol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Belatacept belongs to Miscellaneous; Certolizumab pegol belongs to Musculoskeletal.
為什麼會發生
Additive immunosuppression via TNF-alpha blockade and T-cell costimulation blockade.
處置方式
Avoid combining unless clearly necessary. If combined, monitor closely for infection and screen for latent tuberculosis and hepatitis B.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Certolizumab pegol 的其他交互作用
- Adenovirus types 4 and 7 live + Certolizumab pegol 禁忌併用
- Bcg intravesical live + Certolizumab pegol 禁忌併用
- Bcg vaccine live + Certolizumab pegol 禁忌併用
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Certolizumab pegol + Measles mumps and rubella vaccine 禁忌併用
- Certolizumab pegol + Measles mumps and rubella vaccine live 禁忌併用
Belatacept 的其他交互作用
常見問題
Can I take Belatacept with Certolizumab pegol?
MediHelp rates the interaction as major. Belatacept and Certolizumab pegol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both agents suppress immune function, so combining them raises the risk of serious infections and possibly malignancy, including post-transplant lymphoproliferative disorder with belatacept.
How serious is the interaction between Belatacept and Certolizumab pegol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining unless clearly necessary. If combined, monitor closely for infection and screen for latent tuberculosis and hepatitis B.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
