藥物交互作用
Certolizumab pegol + Measles mumps and rubella vaccine
嚴重程度: 禁忌併用
Certolizumab pegol and Measles mumps and rubella vaccine: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The live attenuated vaccine relies on a competent immune system to limit viral replication, and certolizumab pegol (a TNF-alpha antagonist) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.
用白話說明這項交互作用的意義
Certolizumab pegol and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Certolizumab pegol belongs to Musculoskeletal; Measles mumps and rubella vaccine belongs to Miscellaneous.
為什麼會發生
Certolizumab pegol-mediated immunosuppression allows replication of a live attenuated virus
處置方式
Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Measles mumps and rubella vaccine 的其他交互作用
- Adalimumab + Measles mumps and rubella vaccine 禁忌併用
- Anakinra + Measles mumps and rubella vaccine 禁忌併用
- Antithymocyte globulin equine + Measles mumps and rubella vaccine 禁忌併用
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine 禁忌併用
- Azathioprine + Measles mumps and rubella vaccine 禁忌併用
- Basiliximab + Measles mumps and rubella vaccine 禁忌併用
Certolizumab pegol 的其他交互作用
- Adenovirus types 4 and 7 live + Certolizumab pegol 禁忌併用
- Bcg intravesical live + Certolizumab pegol 禁忌併用
- Bcg vaccine live + Certolizumab pegol 禁忌併用
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Certolizumab pegol + Measles mumps and rubella vaccine live 禁忌併用
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live 禁忌併用
常見問題
Can I take Certolizumab pegol with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live attenuated vaccine relies on a competent immune system to limit viral replication, and certolizumab pegol (a TNF-alpha antagonist) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.
How serious is the interaction between Certolizumab pegol and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
