藥物交互作用
Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal
嚴重程度: 禁忌併用
Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The intranasal influenza vaccine is a live attenuated product. In patients on certolizumab, the vaccine virus may replicate in an uncontrolled way and cause vaccine-related illness, while immune response may be reduced.
用白話說明這項交互作用的意義
Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
TNF blockade-related immunosuppression reduces control of replicating attenuated influenza virus.
處置方式
Use the inactivated injectable influenza vaccine instead of the intranasal live vaccine in patients on certolizumab.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Certolizumab pegol 的其他交互作用
- Adenovirus types 4 and 7 live + Certolizumab pegol 禁忌併用
- Bcg intravesical live + Certolizumab pegol 禁忌併用
- Bcg vaccine live + Certolizumab pegol 禁忌併用
- Certolizumab pegol + Measles mumps and rubella vaccine 禁忌併用
- Certolizumab pegol + Measles mumps and rubella vaccine live 禁忌併用
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live 禁忌併用
常見問題
Can I take Certolizumab pegol with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine is a live attenuated product. In patients on certolizumab, the vaccine virus may replicate in an uncontrolled way and cause vaccine-related illness, while immune response may be reduced.
How serious is the interaction between Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the inactivated injectable influenza vaccine instead of the intranasal live vaccine in patients on certolizumab.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
