藥物交互作用
Belladonna and opium + Glycopyrronium
嚴重程度: 中度
Belladonna and opium and Glycopyrronium: moderate interaction.
最後更新
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摘要
Belladonna and opium suppositories combine an antimuscarinic with an opioid, and with glycopyrronium the anticholinergic and constipating effects add up. Urinary retention, severe constipation and paralytic ileus can result.
用白話說明這項交互作用的意義
Belladonna and opium and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive antimuscarinic effects, with opioid-induced reduction of gut and bladder motility compounding them.
處置方式
Monitor bowel function and urinary output, and avoid the combination in patients with ileus risk or urinary obstruction.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Glycopyrronium 的其他交互作用
常見問題
Can I take Belladonna and opium with Glycopyrronium?
MediHelp rates the interaction as moderate. Belladonna and opium and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Belladonna and opium suppositories combine an antimuscarinic with an opioid, and with glycopyrronium the anticholinergic and constipating effects add up. Urinary retention, severe constipation and paralytic ileus can result.
How serious is the interaction between Belladonna and opium and Glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor bowel function and urinary output, and avoid the combination in patients with ileus risk or urinary obstruction.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Glycopyrronium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
