藥物交互作用
Benzathine penicillin g + Cholera vaccine
嚴重程度: 中度
Benzathine penicillin g and Cholera vaccine: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The oral live attenuated cholera vaccine contains a live bacterial strain that may be killed by systemic antibiotics, reducing the immune response. Penicillin G activity against Vibrio cholerae may impair vaccine take.
用白話說明這項交互作用的意義
Benzathine penicillin g and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibacterial activity against the live attenuated vaccine strain reduces replication and immunogenicity.
處置方式
Do not give the vaccine to patients who have taken systemic antibiotics within the prior 14 days, per labeling. Delay vaccination until the antibiotic course is finished.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Benzathine penicillin g 的其他交互作用
常見問題
Can I take Benzathine penicillin g with Cholera vaccine?
MediHelp rates the interaction as moderate. Benzathine penicillin g and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine contains a live bacterial strain that may be killed by systemic antibiotics, reducing the immune response. Penicillin G activity against Vibrio cholerae may impair vaccine take.
How serious is the interaction between Benzathine penicillin g and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the vaccine to patients who have taken systemic antibiotics within the prior 14 days, per labeling. Delay vaccination until the antibiotic course is finished.
What other medicines interact with Benzathine penicillin g?
MediHelp also lists interactions of Benzathine penicillin g with, for example, Microbiota, Omadacycline, Sodium picosulfate / magnesium oxide / anhydrous citric acid. The full list is on the Benzathine penicillin g page.
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