藥物交互作用
Benzathine penicillin g + Microbiota
嚴重程度: 中度
Benzathine penicillin g and Microbiota: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Oral microbiota products contain live bacterial spores intended to recolonize the gut. Concurrent penicillin can act against them and reduce engraftment and effectiveness, although benzathine penicillin has a prolonged presence after injection.
用白話說明這項交互作用的意義
Benzathine penicillin g and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibacterial activity of penicillin against the live microbiota components reduces colonization (pharmacodynamic antagonism).
處置方式
Complete antibiotic therapy and wait at least 2 to 4 days before giving oral microbiota. Because benzathine penicillin persists for weeks, consider timing the product with this in mind.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Benzathine penicillin g 的其他交互作用
常見問題
Can I take Benzathine penicillin g with Microbiota?
MediHelp rates the interaction as moderate. Benzathine penicillin g and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota products contain live bacterial spores intended to recolonize the gut. Concurrent penicillin can act against them and reduce engraftment and effectiveness, although benzathine penicillin has a prolonged presence after injection.
How serious is the interaction between Benzathine penicillin g and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete antibiotic therapy and wait at least 2 to 4 days before giving oral microbiota. Because benzathine penicillin persists for weeks, consider timing the product with this in mind.
What other medicines interact with Benzathine penicillin g?
MediHelp also lists interactions of Benzathine penicillin g with, for example, Cholera vaccine, Omadacycline, Sodium picosulfate / magnesium oxide / anhydrous citric acid. The full list is on the Benzathine penicillin g page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。