藥物交互作用
Baricitinib + Benzathine penicillin g
嚴重程度: 輕微
Baricitinib and Benzathine penicillin g: minor interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Penicillins can inhibit OAT3, a transporter involved in baricitinib renal elimination, so baricitinib exposure may rise. Labeling advises against strong OAT3 inhibitors such as probenecid, but penicillin G is a much weaker inhibitor and benzathine penicillin gives low sustained levels, so the effect is likely small.
用白話說明這項交互作用的意義
Baricitinib and Benzathine penicillin g have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Baricitinib belongs to Musculoskeletal; Benzathine penicillin g belongs to Anti Bacterial.
為什麼會發生
Possible weak OAT3 inhibition reducing renal tubular secretion of baricitinib.
處置方式
No dose change is generally needed; monitor for baricitinib adverse effects such as infection and cytopenias as usual.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Benzathine penicillin g 的其他交互作用
Baricitinib 的其他交互作用
常見問題
Can I take Baricitinib with Benzathine penicillin g?
MediHelp rates the interaction as minor. Baricitinib and Benzathine penicillin g have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Penicillins can inhibit OAT3, a transporter involved in baricitinib renal elimination, so baricitinib exposure may rise. Labeling advises against strong OAT3 inhibitors such as probenecid, but penicillin G is a much weaker inhibitor and benzathine penicillin gives low sustained levels, so the effect is likely small.
How serious is the interaction between Baricitinib and Benzathine penicillin g?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is generally needed; monitor for baricitinib adverse effects such as infection and cytopenias as usual.
What other medicines interact with Benzathine penicillin g?
MediHelp also lists interactions of Benzathine penicillin g with, for example, Cholera vaccine, Microbiota, Omadacycline. The full list is on the Benzathine penicillin g page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
