藥物交互作用
Cabotegravir + Dolutegravir
嚴重程度: 嚴重
Cabotegravir and Dolutegravir: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Both are integrase strand transfer inhibitors, so the combination duplicates therapy without established benefit. Cabotegravir with rilpivirine is designed as a complete regimen.
用白話說明這項交互作用的意義
Cabotegravir and Dolutegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cabotegravir belongs to Anti Virals; Dolutegravir belongs to Anti Virals.
為什麼會發生
Pharmacodynamic duplication of integrase inhibitor therapy, with no established combination benefit.
處置方式
Do not combine; use a single integrase inhibitor within a complete regimen.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Dolutegravir 的其他交互作用
Cabotegravir 的其他交互作用
常見問題
Can I take Cabotegravir with Dolutegravir?
MediHelp rates the interaction as major. Cabotegravir and Dolutegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both are integrase strand transfer inhibitors, so the combination duplicates therapy without established benefit. Cabotegravir with rilpivirine is designed as a complete regimen.
How serious is the interaction between Cabotegravir and Dolutegravir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use a single integrase inhibitor within a complete regimen.
What other medicines interact with Dolutegravir?
MediHelp also lists interactions of Dolutegravir with, for example, Dofetilide, Aluminum hydroxide, Atidarsagene autotemcel. The full list is on the Dolutegravir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。