藥物交互作用
Calcifediol + Carbamazepine
嚴重程度: 中度
Calcifediol and Carbamazepine: moderate interaction.
最後更新
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摘要
Carbamazepine accelerates vitamin D metabolism, which may shorten calcifediol half-life and lower its effect. Long-term anticonvulsant use is associated with reduced vitamin D status and bone loss.
用白話說明這項交互作用的意義
Calcifediol and Carbamazepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcifediol belongs to Musculoskeletal; Carbamazepine belongs to Central Nervous System.
為什麼會發生
Carbamazepine induces hepatic enzymes that hydroxylate and inactivate vitamin D metabolites.
處置方式
Monitor serum 25-hydroxyvitamin D, calcium and PTH, and increase the calcifediol dose as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Carbamazepine 的其他交互作用
Calcifediol 的其他交互作用
常見問題
Can I take Calcifediol with Carbamazepine?
MediHelp rates the interaction as moderate. Calcifediol and Carbamazepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbamazepine accelerates vitamin D metabolism, which may shorten calcifediol half-life and lower its effect. Long-term anticonvulsant use is associated with reduced vitamin D status and bone loss.
How serious is the interaction between Calcifediol and Carbamazepine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum 25-hydroxyvitamin D, calcium and PTH, and increase the calcifediol dose as needed.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
