藥物交互作用
Carbidopa-levodopa + Ferric maltol
嚴重程度: 中度
Carbidopa-levodopa and Ferric maltol: moderate interaction.
最後更新
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摘要
Oral iron binds levodopa in the gut, reducing its absorption and potentially lessening its effect, with worse motor control in some patients. This applies to oral ferric maltol.
用白話說明這項交互作用的意義
Carbidopa-levodopa and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbidopa-levodopa belongs to Central Nervous System; Ferric maltol belongs to Miscellaneous.
為什麼會發生
Chelation of levodopa by iron in the gastrointestinal tract, reducing absorption.
處置方式
Separate doses by at least 2 hours and monitor motor response. Adjust the levodopa dose if symptoms worsen.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Carbidopa-levodopa 的其他交互作用
Ferric maltol 的其他交互作用
常見問題
Can I take Carbidopa-levodopa with Ferric maltol?
MediHelp rates the interaction as moderate. Carbidopa-levodopa and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron binds levodopa in the gut, reducing its absorption and potentially lessening its effect, with worse motor control in some patients. This applies to oral ferric maltol.
How serious is the interaction between Carbidopa-levodopa and Ferric maltol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least 2 hours and monitor motor response. Adjust the levodopa dose if symptoms worsen.
What other medicines interact with Carbidopa-levodopa?
MediHelp also lists interactions of Carbidopa-levodopa with, for example, Isocarboxazid, Phenelzine, Selegiline transdermal. The full list is on the Carbidopa-levodopa page.
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