藥物交互作用
Carmustine + Lomustine
嚴重程度: 嚴重
Carmustine and Lomustine: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Both are nitrosoureas with delayed, cumulative myelosuppression and pulmonary toxicity. Using them together increases the risk of profound and prolonged cytopenias and lung injury. There is no therapeutic rationale for combining agents of the same class.
用白話說明這項交互作用的意義
Carmustine and Lomustine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Carmustine belongs to Oncology; Lomustine belongs to Oncology.
為什麼會發生
Additive alkylating cytotoxicity affecting bone marrow and lung tissue.
處置方式
Avoid concurrent use where possible. If sequential use is needed, monitor blood counts weekly for several weeks and check pulmonary function.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Lomustine 的其他交互作用
- Adenovirus types 4 and 7 live + Lomustine 禁忌併用
- Bcg vaccine live + Lomustine 禁忌併用
- Influenza virus vaccine quadrivalent intranasal + Lomustine 禁忌併用
- Lomustine + Measles mumps and rubella vaccine 禁忌併用
- Lomustine + Measles mumps and rubella vaccine live 禁忌併用
- Lomustine + Measles mumps rubella and varicella vaccine live 禁忌併用
Carmustine 的其他交互作用
常見問題
Can I take Carmustine with Lomustine?
MediHelp rates the interaction as major. Carmustine and Lomustine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both are nitrosoureas with delayed, cumulative myelosuppression and pulmonary toxicity. Using them together increases the risk of profound and prolonged cytopenias and lung injury. There is no therapeutic rationale for combining agents of the same class.
How serious is the interaction between Carmustine and Lomustine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible. If sequential use is needed, monitor blood counts weekly for several weeks and check pulmonary function.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
