藥物交互作用
Cefepime + Dexamethasone-tobramycin
嚴重程度: 中度
Cefepime and Dexamethasone-tobramycin: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Cefepime combined with an aminoglycoside may increase the risk of kidney injury, and renal impairment in turn raises the risk of cefepime neurotoxicity. Combination therapy is common but warrants attention to renal function.
用白話說明這項交互作用的意義
Cefepime and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefepime belongs to Anti Bacterial; Dexamethasone-tobramycin belongs to Anti Bacterial.
為什麼會發生
Possible additive nephrotoxicity; mechanism not firmly established.
處置方式
Monitor serum creatinine and tobramycin levels, and adjust cefepime dose for renal function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Dexamethasone-tobramycin 的其他交互作用
Cefepime 的其他交互作用
常見問題
Can I take Cefepime with Dexamethasone-tobramycin?
MediHelp rates the interaction as moderate. Cefepime and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefepime combined with an aminoglycoside may increase the risk of kidney injury, and renal impairment in turn raises the risk of cefepime neurotoxicity. Combination therapy is common but warrants attention to renal function.
How serious is the interaction between Cefepime and Dexamethasone-tobramycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and tobramycin levels, and adjust cefepime dose for renal function.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
