藥品參考
Cefepime
Cefepime is a medicine in the class anti bacterial. It is used for febrile neutropenia.
- 藥物類別: Anti Bacterial
- 用途: febrile neutropenia
最後更新 來源: US FDA label, CIMA AEMPS (Spain), AEMPS CIMA ficha tecnica (Spanish)
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Bacterial
- 常見劑型
- 注射劑
- 常見規格
- 1 g, 2 g, 500 mg
- 已知交互作用
- 22 (中度: 12 · 輕微: 10)
- 商品名
- 47
- 國家與市場
- 4
用途
作用方式
Fourth-generation cephalosporin; has gram-negative coverage comparable to ceftazidime but better gram-positive coverage (comparable to ceftriaxone); is zwitterion and rapidly penetrates gram-negative cells; is best beta-lactam for IM administration; has poor capacity to cross blood-brain barrier and thus is not used for treatment of meningitis
成人常用劑量（仿單摘要）
Pneumonia : 1-2 g IV q8-12hr for 7-10 days (if not caused by Pseudomonas) or for up to 21 days (if caused by Pseudomonas)
懷孕與哺乳
- 懷孕
- Safe Cephalosporins are widely used in pregnancy, and available data show no increase in birth defects; animal studies showed no harm. Considered a safe choice for serious infections.
- 哺乳
- Safe Passes into milk in low amounts. Compatible with breastfeeding; watch the infant for loose stools, rash or thrush.
已通報的副作用
- Diarrhea
- Rash
- Positive Coombs test result without hemolysis
- Elevated alanine aminotransferase
- Hypophosphatemia
禁忌症
- Documented hypersensitivity to cefepime, penicillins, or other beta-lactam antibiotics
哪些人需要特別留意
- If CrCl <60 mL/min, adjust dosage to compensate for slower renal elimination rate
- Caution warranted with history of previous immediate hypersensitivity reactions to cefepime, cephalosporins, penicillins, or other drugs
- Prescribing drug in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to patient
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (22)
- Amikacin + Cefepime Moderate
- Cefepime + Cholera vaccine Moderate
- Cefepime + Dexamethasone-tobramycin Moderate
- Cefepime + Gentamicin Moderate
- Cefepime + Kanamycin Moderate
- Cefepime + Microbiota Moderate
- Cefepime + Plazomicin Moderate
- Cefepime + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderate
- Cefepime + Streptomycin Moderate
- Cefepime + Tobramycin Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Cefepime 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Cefepime used for?
Cefepime is a medicine in the class anti bacterial. It is used for Febrile neutropenia, Intra-abdominal infections, Pneumonia, Sepsis, Skin infections, Urinary tract infections.
What side effects have been reported with Cefepime?
Diarrhea, Rash, Positive Coombs test result without hemolysis, Elevated alanine aminotransferase, Hypophosphatemia.
Can Cefepime be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Cephalosporins are widely used in pregnancy, and available data show no increase in birth defects; animal studies showed no harm. Considered a safe choice for serious infections. Breastfeeding: Safe. Passes into milk in low amounts. Compatible with breastfeeding; watch the infant for loose stools, rash or thrush.
What does Cefepime interact with?
MediHelp lists 22 known interactions for Cefepime. Moderate: 12 · Minor: 10. The most serious include Amikacin, Cholera vaccine, Dexamethasone-tobramycin.
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