藥物交互作用
Cefotetan + Streptomycin
嚴重程度: 中度
Cefotetan and Streptomycin: moderate interaction.
最後更新
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摘要
Streptomycin is nephrotoxic and ototoxic, and cephalosporins have been reported to add to aminoglycoside kidney injury in some patients. Renal impairment would then raise streptomycin levels and the risk of ototoxicity.
用白話說明這項交互作用的意義
Cefotetan and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefotetan belongs to Anti Bacterial; Streptomycin belongs to Anti Bacterial.
為什麼會發生
Possible additive nephrotoxicity, with reduced renal clearance of streptomycin if kidney function declines.
處置方式
Monitor serum creatinine and streptomycin levels, and adjust the streptomycin dose to renal function. Watch for hearing loss or vestibular symptoms.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Streptomycin 的其他交互作用
Cefotetan 的其他交互作用
常見問題
Can I take Cefotetan with Streptomycin?
MediHelp rates the interaction as moderate. Cefotetan and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Streptomycin is nephrotoxic and ototoxic, and cephalosporins have been reported to add to aminoglycoside kidney injury in some patients. Renal impairment would then raise streptomycin levels and the risk of ototoxicity.
How serious is the interaction between Cefotetan and Streptomycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and streptomycin levels, and adjust the streptomycin dose to renal function. Watch for hearing loss or vestibular symptoms.
What other medicines interact with Streptomycin?
MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Adefovir, Amikacin. The full list is on the Streptomycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
