藥物交互作用
Cefpodoxime + Gentamicin
嚴重程度: 中度
Cefpodoxime and Gentamicin: moderate interaction.
最後更新
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摘要
Cephalosporins have been reported to add to aminoglycoside nephrotoxicity, though oral cefpodoxime has low direct renal toxicity. Risk is higher in patients with kidney impairment, older age, or dehydration.
用白話說明這項交互作用的意義
Cefpodoxime and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpodoxime belongs to Anti Bacterial; Gentamicin belongs to Anti Bacterial.
為什麼會發生
Possible additive renal tubular injury; cefpodoxime itself is rarely nephrotoxic.
處置方式
Monitor serum creatinine and gentamicin levels during co-therapy, and adjust gentamicin dosing to renal function. Maintain hydration.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefpodoxime 的其他交互作用
Gentamicin 的其他交互作用
常見問題
Can I take Cefpodoxime with Gentamicin?
MediHelp rates the interaction as moderate. Cefpodoxime and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cephalosporins have been reported to add to aminoglycoside nephrotoxicity, though oral cefpodoxime has low direct renal toxicity. Risk is higher in patients with kidney impairment, older age, or dehydration.
How serious is the interaction between Cefpodoxime and Gentamicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and gentamicin levels during co-therapy, and adjust gentamicin dosing to renal function. Maintain hydration.
What other medicines interact with Cefpodoxime?
MediHelp also lists interactions of Cefpodoxime with, for example, Aluminum hydroxide, Amikacin, Calcium carbonate. The full list is on the Cefpodoxime page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
