藥物交互作用
Certolizumab pegol + Measles mumps rubella and varicella vaccine live
嚴重程度: 禁忌併用
Certolizumab pegol and Measles mumps rubella and varicella vaccine live: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
MMRV vaccine contains four live attenuated viruses. In patients on certolizumab, uncontrolled vaccine virus replication and disseminated disease can occur, and the immune response may be blunted.
用白話說明這項交互作用的意義
Certolizumab pegol and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
TNF inhibition suppresses immunity needed to control attenuated live viruses.
處置方式
Do not use MMRV during certolizumab therapy. Give it at least 4 weeks before starting treatment if possible.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Certolizumab pegol 的其他交互作用
- Adenovirus types 4 and 7 live + Certolizumab pegol 禁忌併用
- Bcg intravesical live + Certolizumab pegol 禁忌併用
- Bcg vaccine live + Certolizumab pegol 禁忌併用
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Certolizumab pegol + Measles mumps and rubella vaccine 禁忌併用
- Certolizumab pegol + Measles mumps and rubella vaccine live 禁忌併用
常見問題
Can I take Certolizumab pegol with Measles mumps rubella and varicella vaccine live?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMRV vaccine contains four live attenuated viruses. In patients on certolizumab, uncontrolled vaccine virus replication and disseminated disease can occur, and the immune response may be blunted.
How serious is the interaction between Certolizumab pegol and Measles mumps rubella and varicella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use MMRV during certolizumab therapy. Give it at least 4 weeks before starting treatment if possible.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
