藥物交互作用
Charcoal + Citalopram
嚴重程度: 中度
Charcoal and Citalopram: moderate interaction.
最後更新
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摘要
Activated charcoal binds citalopram in the gut and reduces its absorption. With therapeutic dosing this could lower efficacy, whereas in overdose this effect is intentionally used to limit toxicity.
用白話說明這項交互作用的意義
Charcoal and Citalopram can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Charcoal belongs to Gastrointestinal Tract; Citalopram belongs to Central Nervous System.
為什麼會發生
Charcoal adsorbs citalopram in the gastrointestinal tract, reducing its absorption.
處置方式
Separate therapeutic citalopram doses from charcoal by at least 2 hours, ideally giving citalopram well before charcoal. In overdose, give charcoal as indicated and monitor ECG and for serotonin toxicity.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Charcoal 的其他交互作用
Citalopram 的其他交互作用
常見問題
Can I take Charcoal with Citalopram?
MediHelp rates the interaction as moderate. Charcoal and Citalopram can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Activated charcoal binds citalopram in the gut and reduces its absorption. With therapeutic dosing this could lower efficacy, whereas in overdose this effect is intentionally used to limit toxicity.
How serious is the interaction between Charcoal and Citalopram?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate therapeutic citalopram doses from charcoal by at least 2 hours, ideally giving citalopram well before charcoal. In overdose, give charcoal as indicated and monitor ECG and for serotonin toxicity.
What other medicines interact with Charcoal?
MediHelp also lists interactions of Charcoal with, for example, Digoxin, Leflunomide, Methotrexate. The full list is on the Charcoal page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
