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藥物交互作用

Charcoal + Theophylline

嚴重程度: 中度

Charcoal and Theophylline: moderate interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Activated charcoal binds theophylline in the gut and increases its elimination, including from the circulation with repeated doses. This reduces bronchodilator effect at therapeutic doses but is valuable in theophylline overdose.

用白話說明這項交互作用的意義

Charcoal and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Charcoal belongs to Gastrointestinal Tract; Theophylline belongs to Respiratory.

證據等級: High

為什麼會發生

Charcoal adsorbs theophylline in the gut and enhances its elimination by gastrointestinal dialysis.

處置方式

Avoid concurrent charcoal during therapeutic theophylline use or separate doses by several hours. In overdose, give repeated-dose charcoal and monitor serum theophylline levels.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Charcoal 與 Theophylline 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Charcoal with Theophylline?

MediHelp rates the interaction as moderate. Charcoal and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Activated charcoal binds theophylline in the gut and increases its elimination, including from the circulation with repeated doses. This reduces bronchodilator effect at therapeutic doses but is valuable in theophylline overdose.

How serious is the interaction between Charcoal and Theophylline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent charcoal during therapeutic theophylline use or separate doses by several hours. In overdose, give repeated-dose charcoal and monitor serum theophylline levels.

What other medicines interact with Charcoal?

MediHelp also lists interactions of Charcoal with, for example, Citalopram, Digoxin, Leflunomide. The full list is on the Charcoal page.

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