藥物交互作用
Chlorpromazine + Glycopyrrolate
嚴重程度: 中度
Chlorpromazine and Glycopyrrolate: moderate interaction.
最後更新
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摘要
Chlorpromazine has anticholinergic properties that add to those of glycopyrrolate. This may cause dry mouth, constipation, urinary retention, blurred vision, tachycardia and confusion, and in severe cases reduced gut motility or ileus.
用白話說明這項交互作用的意義
Chlorpromazine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorpromazine belongs to Central Nervous System; Glycopyrrolate belongs to Respiratory.
為什麼會發生
Additive antimuscarinic (anticholinergic) pharmacodynamic effects.
處置方式
Monitor for anticholinergic adverse effects, especially in older patients, and for constipation or urinary retention. Reduce the dose of one agent or choose an alternative if symptoms become troublesome.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Chlorpromazine 的其他交互作用
Glycopyrrolate 的其他交互作用
常見問題
Can I take Chlorpromazine with Glycopyrrolate?
MediHelp rates the interaction as moderate. Chlorpromazine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chlorpromazine has anticholinergic properties that add to those of glycopyrrolate. This may cause dry mouth, constipation, urinary retention, blurred vision, tachycardia and confusion, and in severe cases reduced gut motility or ileus.
How serious is the interaction between Chlorpromazine and Glycopyrrolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects, especially in older patients, and for constipation or urinary retention. Reduce the dose of one agent or choose an alternative if symptoms become troublesome.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Droperidol. The full list is on the Chlorpromazine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
