藥物交互作用
Atropine + Glycopyrrolate
嚴重程度: 中度
Atropine and Glycopyrrolate: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Both are antimuscarinic drugs, so combined use duplicates therapy and increases anticholinergic effects. Patients may develop dry mouth, tachycardia, urinary retention, constipation and blurred vision.
用白話說明這項交互作用的意義
Atropine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Glycopyrrolate belongs to Respiratory.
為什麼會發生
Additive muscarinic receptor antagonism.
處置方式
Avoid duplicate antimuscarinic therapy unless clinically intended, for example in anesthesia. Monitor heart rate, bowel and bladder function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Atropine 的其他交互作用
Glycopyrrolate 的其他交互作用
常見問題
Can I take Atropine with Glycopyrrolate?
MediHelp rates the interaction as moderate. Atropine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinic drugs, so combined use duplicates therapy and increases anticholinergic effects. Patients may develop dry mouth, tachycardia, urinary retention, constipation and blurred vision.
How serious is the interaction between Atropine and Glycopyrrolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid duplicate antimuscarinic therapy unless clinically intended, for example in anesthesia. Monitor heart rate, bowel and bladder function.
What other medicines interact with Atropine?
MediHelp also lists interactions of Atropine with, for example, Eluxadoline, Henbane, Pramlintide. The full list is on the Atropine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
