藥物交互作用
Chlorthalidone + Ergocalciferol
嚴重程度: 中度
Chlorthalidone and Ergocalciferol: moderate interaction.
最後更新
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摘要
Thiazide-type diuretics reduce urinary calcium excretion, and with vitamin D this may lead to hypercalcemia. The risk is greater with high vitamin D doses or in hypoparathyroidism and renal impairment.
用白話說明這項交互作用的意義
Chlorthalidone and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorthalidone belongs to Cardiovascular; Ergocalciferol belongs to Musculoskeletal.
為什麼會發生
Chlorthalidone decreases renal calcium excretion, adding to the increased calcium absorption caused by vitamin D.
處置方式
Monitor serum calcium, especially after starting or changing doses. Reduce vitamin D dose if hypercalcemia develops.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ergocalciferol 的其他交互作用
Chlorthalidone 的其他交互作用
常見問題
Can I take Chlorthalidone with Ergocalciferol?
MediHelp rates the interaction as moderate. Chlorthalidone and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide-type diuretics reduce urinary calcium excretion, and with vitamin D this may lead to hypercalcemia. The risk is greater with high vitamin D doses or in hypoparathyroidism and renal impairment.
How serious is the interaction between Chlorthalidone and Ergocalciferol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium, especially after starting or changing doses. Reduce vitamin D dose if hypercalcemia develops.
What other medicines interact with Ergocalciferol?
MediHelp also lists interactions of Ergocalciferol with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ergocalciferol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
