藥物交互作用
Cholestyramine + Cholic acid
嚴重程度: 嚴重
Cholestyramine and Cholic acid: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Bile acid sequestrants bind cholic acid in the intestine and prevent its absorption. This can reduce the efficacy of cholic acid replacement therapy in bile acid synthesis disorders.
用白話說明這項交互作用的意義
Cholestyramine and Cholic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cholestyramine belongs to Cardiovascular; Cholic acid belongs to Gastrointestinal Tract.
為什麼會發生
Cholestyramine binds bile acids in the gut lumen, preventing their absorption.
處置方式
Take cholic acid at least 1 hour before or 4-6 hours after cholestyramine. Monitor liver tests and bile acid response.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cholestyramine 的其他交互作用
Cholic acid 的其他交互作用
常見問題
Can I take Cholestyramine with Cholic acid?
MediHelp rates the interaction as major. Cholestyramine and Cholic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Bile acid sequestrants bind cholic acid in the intestine and prevent its absorption. This can reduce the efficacy of cholic acid replacement therapy in bile acid synthesis disorders.
How serious is the interaction between Cholestyramine and Cholic acid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take cholic acid at least 1 hour before or 4-6 hours after cholestyramine. Monitor liver tests and bile acid response.
What other medicines interact with Cholestyramine?
MediHelp also lists interactions of Cholestyramine with, for example, Deferasirox, Leflunomide, Levothyroxine. The full list is on the Cholestyramine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
