藥物交互作用
Clotrimazole + Everolimus
嚴重程度: 中度
Clotrimazole and Everolimus: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Clotrimazole (oral troche and vaginal products with systemic absorption) can inhibit CYP3A4 and P-glycoprotein and may raise everolimus levels. Higher everolimus exposure increases the risk of mucositis, infection and metabolic effects.
用白話說明這項交互作用的意義
Clotrimazole and Everolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Clotrimazole belongs to Anti Fungals; Everolimus belongs to Oncology.
為什麼會發生
CYP3A4 and P-gp inhibition may raise everolimus exposure
處置方式
Monitor everolimus trough levels and avoid prolonged oral clotrimazole use; topical use has minimal effect.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Clotrimazole 的其他交互作用
Everolimus 的其他交互作用
常見問題
Can I take Clotrimazole with Everolimus?
MediHelp rates the interaction as moderate. Clotrimazole and Everolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Clotrimazole (oral troche and vaginal products with systemic absorption) can inhibit CYP3A4 and P-glycoprotein and may raise everolimus levels. Higher everolimus exposure increases the risk of mucositis, infection and metabolic effects.
How serious is the interaction between Clotrimazole and Everolimus?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor everolimus trough levels and avoid prolonged oral clotrimazole use; topical use has minimal effect.
What other medicines interact with Clotrimazole?
MediHelp also lists interactions of Clotrimazole with, for example, Lomitapide, Mavacamten, Mobocertinib. The full list is on the Clotrimazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
