藥品參考
Clotrimazole
Clotrimazole is a medicine in the class anti fungals. It is used for candidiasis.
- 藥物類別: Anti Fungals
- 用途: candidiasis
最後更新 來源: US FDA label, UK SmPC
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Fungals
- 常見劑型
- 乳膏, 溶液, 錠劑, 軟膏, 噴霧劑, 粉劑
- 常見規格
- 1 g/100 g, 10 mg/g, 1%
- 已知交互作用
- 32 (嚴重: 4 · 中度: 19 · 輕微: 9)
- 商品名
- 176
- 國家與市場
- 5
用途
作用方式
Antifungal activity Alters cell membrane permeability, apparently by binding with phospholipids in the fungal cell membrane, causing essential intracellular elements to leak
成人常用劑量（仿單摘要）
Opharyngeal candidiasis (prophylaxis): 10 mg PO slowly dissolved in mouth tid or until steroids reduced to maintenance levels
懷孕與哺乳
- 懷孕
- Safe Vaginal, skin and mouth forms give very little absorption, and studies show no rise in birth defects. A 7-day vaginal course is a preferred treatment for thrush in pregnancy; in late pregnancy insert pessaries by hand or with care.
- 哺乳
- Safe Very little is absorbed from skin, vagina or mouth, so it is not expected in milk in meaningful amounts. Compatible with breastfeeding. If used on the nipple for thrush, wipe off before feeds.
已通報的副作用
- Edema
- Pruritus
- Erythema
- Blistering
禁忌症
- Hypersensitivity to clotrimazole or to any of the excipients in the formulation.
哪些人需要特別留意
- Condoms and diagrams may damage and fail to prevent pregnancy or sexually transmitted disease
- Not for use when having vaginal intercourse
- May cause mild increase in vaginal burning, itching or irritation
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (32)
- Clotrimazole + Lomitapide Major
- Clotrimazole + Mavacamten Major
- Clotrimazole + Mobocertinib Major
- Clotrimazole + Voclosporin Major
- Bosutinib + Clotrimazole Moderate
- Cannabidiol + Clotrimazole Moderate
- Clotrimazole + Cyclosporine Moderate
- Clotrimazole + Eliglustat Moderate
- Clotrimazole + Entrectinib Moderate
- Clotrimazole + Everolimus Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Clotrimazole 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同類別的其他藥品
常見問題
What is Clotrimazole used for?
Clotrimazole is a medicine in the class anti fungals. It is used for Candidiasis, Superficial dermatologic infection, Tinea, Vulvovaginal candidiasis.
What side effects have been reported with Clotrimazole?
Edema, Pruritus, Erythema, Blistering.
Can Clotrimazole be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Vaginal, skin and mouth forms give very little absorption, and studies show no rise in birth defects. A 7-day vaginal course is a preferred treatment for thrush in pregnancy; in late pregnancy insert pessaries by hand or with care. Breastfeeding: Safe. Very little is absorbed from skin, vagina or mouth, so it is not expected in milk in meaningful amounts. Compatible with breastfeeding. If used on the nipple for thrush, wipe off before feeds.
What does Clotrimazole interact with?
MediHelp lists 32 known interactions for Clotrimazole. Major: 4 · Moderate: 19 · Minor: 9. The most serious include Lomitapide, Mavacamten, Mobocertinib.
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