藥物交互作用
Copper + Penicillamine
嚴重程度: 中度
Copper and Penicillamine: moderate interaction.
最後更新
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摘要
Penicillamine is used to remove copper in Wilson disease, so copper supplements would work directly against its purpose. Oral copper may also be chelated in the gut, so neither achieves its intended effect.
用白話說明這項交互作用的意義
Copper and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Copper belongs to Gastrointestinal Tract; Penicillamine belongs to Musculoskeletal.
為什麼會發生
Pharmacodynamic antagonism, since penicillamine chelates copper and promotes its urinary excretion.
處置方式
Avoid copper supplements in patients treated with penicillamine for copper overload. In other uses, such as rheumatoid arthritis, separate doses and monitor copper status.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Penicillamine 的其他交互作用
Copper 的其他交互作用
常見問題
Can I take Copper with Penicillamine?
MediHelp rates the interaction as moderate. Copper and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Penicillamine is used to remove copper in Wilson disease, so copper supplements would work directly against its purpose. Oral copper may also be chelated in the gut, so neither achieves its intended effect.
How serious is the interaction between Copper and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid copper supplements in patients treated with penicillamine for copper overload. In other uses, such as rheumatoid arthritis, separate doses and monitor copper status.
What other medicines interact with Penicillamine?
MediHelp also lists interactions of Penicillamine with, for example, Gold sodium thiomalate, Aluminum hydroxide, Calcium carbonate. The full list is on the Penicillamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。