藥物交互作用
Aluminum hydroxide + Penicillamine
嚴重程度: 中度
Aluminum hydroxide and Penicillamine: moderate interaction.
最後更新
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摘要
Aluminum-containing antacids reduce the absorption of penicillamine, which can lower its therapeutic effect in Wilson disease, cystinuria or rheumatoid arthritis. The effect is clinically relevant when doses are close together.
用白話說明這項交互作用的意義
Aluminum hydroxide and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Penicillamine belongs to Musculoskeletal.
為什麼會發生
Aluminum chelates or adsorbs penicillamine in the gut, reducing its oral absorption.
處置方式
Separate penicillamine and the antacid by at least 2 hours. Monitor clinical response, such as urinary copper or cystine, if antacids are used regularly.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Aluminum hydroxide 的其他交互作用
Penicillamine 的其他交互作用
常見問題
Can I take Aluminum hydroxide with Penicillamine?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminum-containing antacids reduce the absorption of penicillamine, which can lower its therapeutic effect in Wilson disease, cystinuria or rheumatoid arthritis. The effect is clinically relevant when doses are close together.
How serious is the interaction between Aluminum hydroxide and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate penicillamine and the antacid by at least 2 hours. Monitor clinical response, such as urinary copper or cystine, if antacids are used regularly.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
