藥物交互作用
Calcium carbonate + Penicillamine
嚴重程度: 中度
Calcium carbonate and Penicillamine: moderate interaction.
最後更新
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摘要
Antacids and mineral supplements can substantially reduce penicillamine absorption, which may weaken its therapeutic effect. Calcium forms complexes with penicillamine in the gut.
用白話說明這項交互作用的意義
Calcium carbonate and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Penicillamine belongs to Musculoskeletal.
為什麼會發生
Chelation or binding of penicillamine by calcium in the gastrointestinal tract reduces absorption.
處置方式
Take penicillamine on an empty stomach and at least 2 hours apart from calcium carbonate. Monitor clinical response.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Calcium carbonate 的其他交互作用
Penicillamine 的其他交互作用
常見問題
Can I take Calcium carbonate with Penicillamine?
MediHelp rates the interaction as moderate. Calcium carbonate and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antacids and mineral supplements can substantially reduce penicillamine absorption, which may weaken its therapeutic effect. Calcium forms complexes with penicillamine in the gut.
How serious is the interaction between Calcium carbonate and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take penicillamine on an empty stomach and at least 2 hours apart from calcium carbonate. Monitor clinical response.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
