藥物交互作用
Carbonyl iron + Penicillamine
嚴重程度: 中度
Carbonyl iron and Penicillamine: moderate interaction.
最後更新
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摘要
Oral iron binds penicillamine in the gut and can substantially reduce its absorption, which may lead to reduced therapeutic effect. Stopping iron can later increase penicillamine exposure.
用白話說明這項交互作用的意義
Carbonyl iron and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Penicillamine belongs to Musculoskeletal.
為什麼會發生
Chelation of penicillamine by iron in the gastrointestinal tract reduces absorption.
處置方式
Separate doses by at least 2 hours, giving penicillamine on an empty stomach. Monitor clinical response and adjust the dose if iron is started or stopped.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Penicillamine 的其他交互作用
Carbonyl iron 的其他交互作用
常見問題
Can I take Carbonyl iron with Penicillamine?
MediHelp rates the interaction as moderate. Carbonyl iron and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron binds penicillamine in the gut and can substantially reduce its absorption, which may lead to reduced therapeutic effect. Stopping iron can later increase penicillamine exposure.
How serious is the interaction between Carbonyl iron and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least 2 hours, giving penicillamine on an empty stomach. Monitor clinical response and adjust the dose if iron is started or stopped.
What other medicines interact with Penicillamine?
MediHelp also lists interactions of Penicillamine with, for example, Gold sodium thiomalate, Aluminum hydroxide, Calcium carbonate. The full list is on the Penicillamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
