藥物交互作用
Digoxin + Penicillamine
嚴重程度: 中度
Digoxin and Penicillamine: moderate interaction.
最後更新
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摘要
Penicillamine has been reported to lower serum digoxin concentrations, which could reduce control of heart rate or heart failure symptoms. The reports are limited and the mechanism is uncertain.
用白話說明這項交互作用的意義
Digoxin and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Digoxin belongs to Cardiovascular; Penicillamine belongs to Musculoskeletal.
為什麼會發生
Mechanism not established; reduced digoxin absorption has been suggested.
處置方式
Monitor serum digoxin levels and clinical response when penicillamine is started or stopped. Increase the digoxin dose if needed, and separate dosing times.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Penicillamine 的其他交互作用
Digoxin 的其他交互作用
常見問題
Can I take Digoxin with Penicillamine?
MediHelp rates the interaction as moderate. Digoxin and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Penicillamine has been reported to lower serum digoxin concentrations, which could reduce control of heart rate or heart failure symptoms. The reports are limited and the mechanism is uncertain.
How serious is the interaction between Digoxin and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum digoxin levels and clinical response when penicillamine is started or stopped. Increase the digoxin dose if needed, and separate dosing times.
What other medicines interact with Penicillamine?
MediHelp also lists interactions of Penicillamine with, for example, Gold sodium thiomalate, Aluminum hydroxide, Calcium carbonate. The full list is on the Penicillamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
