藥物交互作用
Calcium + Penicillamine
嚴重程度: 中度
Calcium and Penicillamine: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Calcium-containing products can reduce oral penicillamine absorption, potentially lessening its therapeutic effect in Wilson disease, cystinuria or rheumatoid arthritis.
用白話說明這項交互作用的意義
Calcium and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium belongs to Gastrointestinal Tract; Penicillamine belongs to Musculoskeletal.
為什麼會發生
Divalent cations chelate penicillamine in the gut, reducing absorption.
處置方式
Take penicillamine on an empty stomach at least 2 hours apart from calcium products. Monitor clinical response and urinary copper or cystine as relevant.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Calcium 的其他交互作用
Penicillamine 的其他交互作用
常見問題
Can I take Calcium with Penicillamine?
MediHelp rates the interaction as moderate. Calcium and Penicillamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium-containing products can reduce oral penicillamine absorption, potentially lessening its therapeutic effect in Wilson disease, cystinuria or rheumatoid arthritis.
How serious is the interaction between Calcium and Penicillamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take penicillamine on an empty stomach at least 2 hours apart from calcium products. Monitor clinical response and urinary copper or cystine as relevant.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
