藥物交互作用
Cyclizine + Glycopyrrolate
嚴重程度: 中度
Cyclizine and Glycopyrrolate: moderate interaction.
最後更新
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摘要
Both drugs have antimuscarinic activity, so combined use increases dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with glaucoma or obstructive conditions are most at risk.
用白話說明這項交互作用的意義
Cyclizine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cyclizine belongs to Respiratory; Glycopyrrolate belongs to Respiratory.
為什麼會發生
Additive muscarinic receptor antagonism.
處置方式
Monitor for anticholinergic effects and reduce doses or choose a non-anticholinergic antiemetic if they occur.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cyclizine 的其他交互作用
Glycopyrrolate 的其他交互作用
常見問題
Can I take Cyclizine with Glycopyrrolate?
MediHelp rates the interaction as moderate. Cyclizine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have antimuscarinic activity, so combined use increases dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with glaucoma or obstructive conditions are most at risk.
How serious is the interaction between Cyclizine and Glycopyrrolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects and reduce doses or choose a non-anticholinergic antiemetic if they occur.
What other medicines interact with Cyclizine?
MediHelp also lists interactions of Cyclizine with, for example, Calcium / magnesium / potassium / sodium oxybates, Henbane, Sodium oxybate. The full list is on the Cyclizine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
