藥物交互作用
Dapagliflozin + Lonapegsomatropin
嚴重程度: 中度
Dapagliflozin and Lonapegsomatropin: moderate interaction.
最後更新
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摘要
Growth hormone products such as lonapegsomatropin can reduce insulin sensitivity, particularly at higher doses. In patients with diabetes this may raise blood glucose and blunt the glucose-lowering effect of dapagliflozin.
用白話說明這項交互作用的意義
Dapagliflozin and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dapagliflozin belongs to Endocrine; Lonapegsomatropin belongs to Endocrine.
為什麼會發生
Pharmacodynamic antagonism: growth hormone induces insulin resistance and opposes the glucose-lowering action of antidiabetic agents.
處置方式
Monitor blood glucose closely when starting or adjusting lonapegsomatropin in patients taking dapagliflozin. Adjust the dose of dapagliflozin or other antihyperglycemic agents as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Dapagliflozin 的其他交互作用
Lonapegsomatropin 的其他交互作用
常見問題
Can I take Dapagliflozin with Lonapegsomatropin?
MediHelp rates the interaction as moderate. Dapagliflozin and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Growth hormone products such as lonapegsomatropin can reduce insulin sensitivity, particularly at higher doses. In patients with diabetes this may raise blood glucose and blunt the glucose-lowering effect of dapagliflozin.
How serious is the interaction between Dapagliflozin and Lonapegsomatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely when starting or adjusting lonapegsomatropin in patients taking dapagliflozin. Adjust the dose of dapagliflozin or other antihyperglycemic agents as needed.
What other medicines interact with Dapagliflozin?
MediHelp also lists interactions of Dapagliflozin with, for example, Chlorpropamide, Gliclazide, Glimepiride. The full list is on the Dapagliflozin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。