藥物交互作用
Dexbrompheniramine + Fentanyl
嚴重程度: 中度
Dexbrompheniramine and Fentanyl: moderate interaction.
最後更新
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摘要
Dexbrompheniramine is a sedating antihistamine that adds to fentanyl's CNS depression. The combination can cause marked drowsiness and impaired psychomotor function, and respiratory depression is possible with higher doses.
用白話說明這項交互作用的意義
Dexbrompheniramine and Fentanyl can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dexbrompheniramine belongs to Respiratory; Fentanyl belongs to Musculoskeletal.
為什麼會發生
Additive CNS depression from an opioid and a sedating first-generation antihistamine.
處置方式
Use the lowest effective doses and monitor for sedation and respiratory depression. Advise patients to avoid alcohol and driving.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Fentanyl 的其他交互作用
Dexbrompheniramine 的其他交互作用
常見問題
Can I take Dexbrompheniramine with Fentanyl?
MediHelp rates the interaction as moderate. Dexbrompheniramine and Fentanyl can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexbrompheniramine is a sedating antihistamine that adds to fentanyl's CNS depression. The combination can cause marked drowsiness and impaired psychomotor function, and respiratory depression is possible with higher doses.
How serious is the interaction between Dexbrompheniramine and Fentanyl?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and monitor for sedation and respiratory depression. Advise patients to avoid alcohol and driving.
What other medicines interact with Fentanyl?
MediHelp also lists interactions of Fentanyl with, for example, Alvimopan, Isocarboxazid, Olanzapine / samidorphan. The full list is on the Fentanyl page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
