藥物交互作用
Dextromoramide + Melatonin
嚴重程度: 中度
Dextromoramide and Melatonin: moderate interaction.
最後更新
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摘要
Dextromoramide is a potent opioid analgesic that causes sedation and respiratory depression, and melatonin may add to drowsiness. Combined use increases the risk of impaired alertness.
用白話說明這項交互作用的意義
Dextromoramide and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive CNS depression from opioid agonism and melatonin-mediated sedation.
處置方式
Use the lowest effective doses and monitor sedation and respiratory rate; counsel against driving.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Melatonin 的其他交互作用
常見問題
Can I take Dextromoramide with Melatonin?
MediHelp rates the interaction as moderate. Dextromoramide and Melatonin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dextromoramide is a potent opioid analgesic that causes sedation and respiratory depression, and melatonin may add to drowsiness. Combined use increases the risk of impaired alertness.
How serious is the interaction between Dextromoramide and Melatonin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and monitor sedation and respiratory rate; counsel against driving.
What other medicines interact with Melatonin?
MediHelp also lists interactions of Melatonin with, for example, Fluvoxamine, Alfentanil, Belladonna and opium. The full list is on the Melatonin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
