藥物交互作用
Dicloxacillin + Isavuconazonium
嚴重程度: 中度
Dicloxacillin and Isavuconazonium: moderate interaction.
最後更新
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摘要
Dicloxacillin is a CYP3A4 inducer and may lower exposure to isavuconazole, the active moiety of isavuconazonium. Reduced antifungal concentrations could compromise treatment of invasive fungal infection.
用白話說明這項交互作用的意義
Dicloxacillin and Isavuconazonium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dicloxacillin belongs to Anti Bacterial; Isavuconazonium belongs to Anti Fungals.
為什麼會發生
Induction of CYP3A4 by dicloxacillin increases isavuconazole metabolism.
處置方式
Monitor clinical response to antifungal therapy and consider isavuconazole trough levels if available; choose an alternative antibacterial if feasible.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Dicloxacillin 的其他交互作用
Isavuconazonium 的其他交互作用
常見問題
Can I take Dicloxacillin with Isavuconazonium?
MediHelp rates the interaction as moderate. Dicloxacillin and Isavuconazonium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dicloxacillin is a CYP3A4 inducer and may lower exposure to isavuconazole, the active moiety of isavuconazonium. Reduced antifungal concentrations could compromise treatment of invasive fungal infection.
How serious is the interaction between Dicloxacillin and Isavuconazonium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to antifungal therapy and consider isavuconazole trough levels if available; choose an alternative antibacterial if feasible.
What other medicines interact with Dicloxacillin?
MediHelp also lists interactions of Dicloxacillin with, for example, Phenindione, Atogepant, Axitinib. The full list is on the Dicloxacillin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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